Human INTS10 activation kit by CRISPRa

SKU GA110575

INTS10 CRISPRa kit - CRISPR gene activation of human integrator complex subunit 10

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: INTS10
• Locus ID: 55174
• Components:

  GA110575G1, INTS10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110575G2, INTS10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110575G3, INTS10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_018142, NM_001353505, NM_001353506, NM_001353507, NM_001353508, NM_001353509, NM_001353510, NM_001353511, NM_001353512, NM_001353513, NM_001353514, NM_001353515, NM_001353516, NM_001353517, NM_001353518, NM_001353519, NM_001353520, NM_001353521, NM_001353522, NR_148451, NR_148452, NR_148453, NR_148454, NR_148455, NR_148456, NR_148457, NR_148458
• UniProt ID: Q9NVR2
• Synonyms: C8orf35; INT10
• Summary: INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]