Human TRIM68 activation kit by CRISPRa

SKU
GA110536
TRIM68 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 68
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRIM68
Locus ID 55128
Components

GA110536G1, TRIM68 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110536G2, TRIM68 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110536G3, TRIM68 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001304496, NM_018073
UniProt ID Q6AZZ1
Synonyms GC109; RNF137; SS-56; SS56
Summary This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN417536 TRIM68 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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