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Human TRMT61B activation kit by CRISPRa

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SKU
GA110445
TRMT61B CRISPRa kit - CRISPR gene activation of human tRNA methyltransferase 61B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA346790 Rabbit Polyclonal Anti-FLJ20628 Antibody
100 ul
$585.00
RC201499 TRMT61B (Myc-DDK-tagged)-Human tRNA methyltransferase 61 homolog B (S. cerevisiae) (TRMT61B)
10 ug
$457.00

Other products for "TRMT61B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRMT61B
Locus ID 55006
Components

GA110445G1, TRMT61B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110445G2, TRMT61B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110445G3, TRMT61B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_017910
UniProt ID Q9BVS5
Synonyms DKFZp564I2178; FLJ20628
Summary Methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (deciphering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (deciphering codons UCA, UCU, UCG or UCC) (PubMed:23097428). Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function (PubMed:27631568). In addition to tRNA N(1)-methyltransferase activity, also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA, leading to interfere with mitochondrial translation (PubMed:29107537).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN401499 TRMT61B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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