Human PINX1 activation kit by CRISPRa

SKU GA110427

PINX1 CRISPRa kit - CRISPR gene activation of human PIN2 (TERF1) interacting telomerase inhibitor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PINX1
• Locus ID: 54984
• Components:

  GA110427G1, PINX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110427G2, PINX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110427G3, PINX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001284356, NM_017884
• UniProt ID: Q96BK5
• Synonyms: LPTL; LPTS
• Summary: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.[UniProtKB/Swiss-Prot Function]