Human ODAM activation kit by CRISPRa

SKU GA110405

ODAM CRISPRa kit - CRISPR gene activation of human odontogenic, ameloblast associated

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ODAM
• Locus ID: 54959
• Components:

  GA110405G1, ODAM gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110405G2, ODAM gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110405G3, ODAM gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_017855
• UniProt ID: A1E959
• Synonyms: APIN
• Summary: Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface.[UniProtKB/Swiss-Prot Function]