Human LIME (LIME1) activation kit by CRISPRa

SKU GA110373

LIME1 CRISPRa kit - CRISPR gene activation of human Lck interacting transmembrane adaptor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LIME1
• Locus ID: 54923
• Components:

  GA110373G1, LIME gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110373G2, LIME gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110373G3, LIME gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001305654, NM_001305655, NM_017806
• UniProt ID: Q9H400
• Synonyms: dJ583P15.4; LIME
• Summary: This gene encodes a transmembrane adaptor protein that links the T and B-cell receptor stimulation to downstream signaling pathways via its association with the Src family kinases Lck and Lyn, respectively. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]