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Human RNF43 activation kit by CRISPRa

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SKU
GA110350
RNF43 CRISPRa kit - CRISPR gene activation of human ring finger protein 43
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA351607 Rabbit Polyclonal Anti-RNF43 Antibody
100 ul
$205.00
RC214013 RNF43 (Myc-DDK-tagged)-Human ring finger protein 43 (RNF43)
10 ug
$1,075.00

Other products for "RNF43"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RNF43
Locus ID 54894
Components

GA110350G1, RNF43 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110350G2, RNF43 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110350G3, RNF43 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001305544, NM_001305545, NM_017763
UniProt ID Q68DV7
Synonyms RNF124; SSPCS; URCC
Summary The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Mar 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN414013 RNF43 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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