Human NDE1 activation kit by CRISPRa

SKU
GA110285
NDE1 CRISPRa kit - CRISPR gene activation of human nudE neurodevelopment protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NDE1
Locus ID 54820
Components

GA110285G1, NDE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110285G2, NDE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110285G3, NDE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001143979, NM_017668
UniProt ID Q9NXR1
Synonyms HOM-TES-87; LIS4; MHAC; NDE; NUDE; NUDE1
Summary This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2012
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Resources
Other Versions
SKU Description Size Price
KN400179 NDE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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