Human TRIT1 activation kit by CRISPRa

CAT#: GA110271

TRIT1 CRISPRa kit - CRISPR gene activation of human tRNA isopentenyltransferase 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TRIT1
• Locus ID: 54802
• Kit Components:

  GA110271G1, TRIT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA110271G2, TRIT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA110271G3, TRIT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001312691, NM_001312692, NM_017646, NR_132401, NR_132402, NR_132403, NR_132404, NR_132405, NR_132406, NR_132407, NR_132408, NR_132409, NR_132410, NR_132412, NR_132413, NR_132414, NR_132415
• UniProt ID: Q9H3H1
• Synonyms: GRO1; hGRO1; IPPT; IPT; IPTase; MOD5
• Summary: This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]