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Human RNF111 activation kit by CRISPRa

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SKU
GA110257
RNF111 CRISPRa kit - CRISPR gene activation of human ring finger protein 111
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA315537 Rabbit polyclonal anti-RNF111 antibody
100 ul
$380.00
RC209308 RNF111 (Myc-DDK-tagged)-Human ring finger protein 111 (RNF111)
10 ug
$589.00 $902.00

Other products for "RNF111"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RNF111
Locus ID 54778
Components

GA110257G1, RNF111 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110257G2, RNF111 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110257G3, RNF111 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001270528, NM_001270529, NM_001270530, NM_017610, NM_001330331, N24855
UniProt ID Q6ZNA4
Synonyms ARK
Summary The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN409308 RNF111 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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