Human MTRF1L activation kit by CRISPRa

SKU
GA110151
MTRF1L CRISPRa kit - CRISPR gene activation of human mitochondrial translational release factor 1 like
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MTRF1L
Locus ID 54516
Components

GA110151G1, MTRF1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110151G2, MTRF1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110151G3, MTRF1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001114184, NM_001301047, NM_001301870, NM_001301871, NM_001301872, NM_019041, NR_126056
UniProt ID Q9UGC7
Synonyms HMRF1L; MRF1L; mtRF1a
Summary The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN404221 MTRF1L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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