Human RAB8B activation kit by CRISPRa

SKU GA109981

RAB8B CRISPRa kit - CRISPR gene activation of human RAB8B, member RAS oncogene family

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RAB8B
• Locus ID: 51762
• Components:

  GA109981G1, RAB8B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109981G2, RAB8B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109981G3, RAB8B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_016530
• UniProt ID: Q92930
• Synonyms: FLJ38125
• Summary: RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010]