Human ARTS1 (ERAP1) activation kit by CRISPRa

SKU
GA109975
ERAP1 CRISPRa kit - CRISPR gene activation of human endoplasmic reticulum aminopeptidase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERAP1
Locus ID 51752
Components

GA109975G1, ARTS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109975G2, ARTS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109975G3, ARTS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001040458, NM_001198541, NM_016442, NM_001349244
UniProt ID Q9NZ08
Synonyms A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP
Summary The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.provided by RefSeq, Oct 2010
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Documents
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Other Versions
SKU Description Size Price
KN405249 ERAP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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