Human WWOX activation kit by CRISPRa

SKU
GA109969
WWOX CRISPRa kit - CRISPR gene activation of human WW domain containing oxidoreductase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WWOX
Locus ID 51741
Components

GA109969G1, WWOX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109969G2, WWOX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109969G3, WWOX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001291997, NM_016373, NM_018560, NM_130788, NM_130790, NM_130791, NM_130792, NM_130844, NR_120435, NR_120436
UniProt ID Q9NZC7
Synonyms D16S432E; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1
Summary This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN412195 WWOX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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