Human VPS54 activation kit by CRISPRa

SKU GA109864

VPS54 CRISPRa kit - CRISPR gene activation of human VPS54 subunit of GARP complex

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: VPS54
• Locus ID: 51542
• Components:

  GA109864G1, VPS54 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109864G2, VPS54 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109864G3, VPS54 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001005739, NM_016516
• UniProt ID: Q9P1Q0
• Synonyms: HCC8; hVps54L; PPP1R164; SLP-8p; VPS54L; WR
• Summary: This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms [provided by RefSeq, Jul 2008]