Human DCDC2 activation kit by CRISPRa

SKU GA109823

DCDC2 CRISPRa kit - CRISPR gene activation of human doublecortin domain containing 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DCDC2
• Locus ID: 51473
• Components:

  GA109823G1, DCDC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109823G2, DCDC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109823G3, DCDC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001195610, NM_016356
• UniProt ID: Q9UHG0
• Synonyms: DCDC2A; NPHP19; RU2; RU2S
• Summary: This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2013]