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Human BAF53b (ACTL6B) activation kit by CRISPRa

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SKU
GA109794
ACTL6B CRISPRa kit - CRISPR gene activation of human actin like 6B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC205358 ACTL6B (Myc-DDK-tagged)-Human actin-like 6B (ACTL6B)
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Other products for "ACTL6B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ACTL6B
Locus ID 51412
Components

GA109794G1, BAF53b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109794G2, BAF53b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109794G3, BAF53b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_016188, NR_134539
UniProt ID O94805
Synonyms ACTL6; BAF53B
Summary The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN405358 ACTL6B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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