Human EDD (UBR5) activation kit by CRISPRa

SKU
GA109767
UBR5 CRISPRa kit - CRISPR gene activation of human ubiquitin protein ligase E3 component n-recognin 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UBR5
Locus ID 51366
Components

GA109767G1, EDD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109767G2, EDD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109767G3, EDD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001282873, NM_015902
UniProt ID O95071
Synonyms DD5; EDD; EDD1; HYD
Summary This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN416868 UBR5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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