Human CRNKL1 activation kit by CRISPRa

SKU GA109754

CRNKL1 CRISPRa kit - CRISPR gene activation of human crooked neck pre-mRNA splicing factor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CRNKL1
• Locus ID: 51340
• Components:

  GA109754G1, CRNKL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109754G2, CRNKL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109754G3, CRNKL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001278625, NM_001278626, NM_001278627, NM_001278628, NM_016652
• UniProt ID: Q9BZJ0
• Synonyms: CLF; Clf1; CRN; HCRN; MSTP021; SYF3
• Summary: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]