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Human MARCHF2 activation kit by CRISPRa

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SKU
GA109682
MARCH2 CRISPRa kit - CRISPR gene activation of human membrane associated ring-CH-type finger 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA315456 Rabbit polyclonal anti-MARCH2 antibody
100 ul
$380.00
RC207517 MARCH2 (Myc-DDK-tagged)-Human membrane-associated ring finger (C3HC4) 2 (MARCH2), transcript variant 1
10 ug
$300.00

Other products for "MARCHF2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MARCHF2
Locus ID 51257
Components

GA109682G1, MARCHF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109682G2, MARCHF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109682G3, MARCHF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001005415, NM_001005416, NM_016496, NM_001369776, NM_001369779, NM_001369777, NM_001369778, NR_163145
UniProt ID Q9P0N8
Synonyms HSPC240; MARCH-II; RNF172
Summary MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 PubMed 14722266; Nakamura et al., 2005 PubMed 15689499).supplied by OMIM, Mar 2010
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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