Human PAIP2 activation kit by CRISPRa

SKU
GA109673
PAIP2 CRISPRa kit - CRISPR gene activation of human poly(A) binding protein interacting protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PAIP2
Locus ID 51247
Components

GA109673G1, PAIP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109673G2, PAIP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109673G3, PAIP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001033112, NM_016480, NR_109830
UniProt ID Q9BPZ3
Synonyms PAIP-2; PAIP2A
Summary Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN407342 PAIP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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