Human ASCC1 activation kit by CRISPRa

SKU
GA109492
ASCC1 CRISPRa kit - CRISPR gene activation of human activating signal cointegrator 1 complex subunit 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ASCC1
Locus ID 51008
Components

GA109492G1, ASCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109492G2, ASCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109492G3, ASCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001198798, NM_001198799, NM_001198800, NM_015947, NR_045564, NM_001369086, NM_001369085, NM_001369087, NM_001369088, NM_001369090, NM_001369091, NM_001369095, NM_001369098, NM_001369099, NM_001369102, NM_001369107, NM_001369110, NM_001369111, NM_001369112, NM_001369089, NM_001369092, NM_001369093, NM_001369094, NM_001369096, NM_001369097, NM_001369100, NM_001369101, NM_001369103, NM_001369104, NM_001369105, NM_001369106, NM_001369108, NM_001369109
UniProt ID Q8N9N2
Synonyms ASC1p50; CGI-18; p50
Summary This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. provided by RefSeq, Dec 2011
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Documents
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Other Versions
SKU Description Size Price
KN401872 ASCC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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