Human MTERFD1 (MTERF3) activation kit by CRISPRa

SKU GA109486

MTERF3 CRISPRa kit - CRISPR gene activation of human mitochondrial transcription termination factor 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MTERF3
• Locus ID: 51001
• Components:

  GA109486G1, MTERFD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109486G2, MTERFD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109486G3, MTERFD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001286643, NM_015942, NM_001362964
• UniProt ID: Q96E29
• Synonyms: CGI-12; MTERFD1
• Summary: Binds promoter DNA and regulates initiation of transcription (PubMed:17662942). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).[UniProtKB/Swiss-Prot Function]