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Human DHH activation kit by CRISPRa

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SKU
GA109466
DHH CRISPRa kit - CRISPR gene activation of human desert hedgehog signaling molecule
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC206715 DHH (Myc-DDK-tagged)-Human desert hedgehog (DHH)
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Other products for "DHH"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DHH
Locus ID 50846
Components

GA109466G1, DHH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109466G2, DHH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109466G3, DHH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_021044
UniProt ID O43323
Synonyms GDXYM; HHG-3; SRXY7
Summary This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. provided by RefSeq, May 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN406715 DHH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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