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Human TNPO2 activation kit by CRISPRa

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SKU
GA109371
TNPO2 CRISPRa kit - CRISPR gene activation of human transportin 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA334486 Rabbit Polyclonal Anti-TNPO2 Antibody
100 ul
$585.00
RC226797 TNPO2 (Myc-DDK-tagged)-Human transportin 2 (TNPO2), transcript variant 1
10 ug
$821.00

Other products for "TNPO2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TNPO2
Locus ID 30000
Components

GA109371G1, TNPO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109371G2, TNPO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109371G3, TNPO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001136195, NM_001136196, NM_013433
UniProt ID O14787
Synonyms IPO3; KPNB2B; TRN2
Summary Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN410064 TNPO2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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