Human DMGDH activation kit by CRISPRa

SKU
GA109342
DMGDH CRISPRa kit - CRISPR gene activation of human dimethylglycine dehydrogenase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DMGDH
Locus ID 29958
Components

GA109342G1, DMGDH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109342G2, DMGDH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109342G3, DMGDH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_013391, NR_104002, NR_104003
UniProt ID Q9UI17
Synonyms DMGDHD; ME2GLYDH
Summary This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
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Other Versions
SKU Description Size Price
KN423089 DMGDH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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