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Human PADI1 activation kit by CRISPRa

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SKU
GA109328
PADI1 CRISPRa kit - CRISPR gene activation of human peptidyl arginine deiminase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC213501 PADI1 (Myc-DDK-tagged)-Human peptidyl arginine deiminase, type I (PADI1)
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Other products for "PADI1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PADI1
Locus ID 29943
Components

GA109328G1, PADI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109328G2, PADI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109328G3, PADI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013358
UniProt ID Q9ULC6
Synonyms HPAD10; PAD1; PDI; PDI1
Summary This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN413501 PADI1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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