Human TIMM22 activation kit by CRISPRa

SKU GA109318

TIMM22 CRISPRa kit - CRISPR gene activation of human translocase of inner mitochondrial membrane 22

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TIMM22
• Locus ID: 29928
• Components:

  GA109318G1, TIMM22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA109318G2, TIMM22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA109318G3, TIMM22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_013337
• UniProt ID: Q9Y584
• Synonyms: TEX4; TIM22
• Summary: Multipass transmembrane proteins are brought into mitochondria and inserted into the mitochondrial inner membrane by way of the TIM22 complex. This complex has six subunits and is a twin-pore translocase. The protein encoded by this gene is a subunit of TIM22 and represents the voltage-activated and signal-gated channel. [provided by RefSeq, Jul 2016]