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Human SNX15 activation kit by CRISPRa

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SKU
GA109304
SNX15 CRISPRa kit - CRISPR gene activation of human sorting nexin 15
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC202594 SNX15 (Myc-DDK-tagged)-Human sorting nexin 15 (SNX15), transcript variant A
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Other products for "SNX15"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SNX15
Locus ID 29907
Components

GA109304G1, SNX15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109304G2, SNX15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109304G3, SNX15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013306, NM_147777
UniProt ID Q9NRS6
Synonyms HSAF001435
Summary This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. provided by RefSeq, Dec 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN402594 SNX15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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