Human C5L2 (C5AR2) activation kit by CRISPRa

SKU
GA109065
C5AR2 CRISPRa kit - CRISPR gene activation of human complement component 5a receptor 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol C5AR2
Locus ID 27202
Components

GA109065G1, C5L2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109065G2, C5L2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109065G3, C5L2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001271749, NM_001271750, NM_018485
UniProt ID Q9P296
Synonyms C5L2; GPF77; GPR77
Summary This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2012
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Other Versions
SKU Description Size Price
KN409676 C5AR2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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