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Human MLH3 activation kit by CRISPRa

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SKU
GA108972
MLH3 CRISPRa kit - CRISPR gene activation of human mutL homolog 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA315357 Rabbit polyclonal anti-MLH3 antibody
100 ul
$380.00
RC212150 MLH3 (Myc-DDK-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2
10 ug
$1,222.00

Other products for "MLH3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MLH3
Locus ID 27030
Components

GA108972G1, MLH3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108972G2, MLH3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108972G3, MLH3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001040108, NM_005784, NM_014381
UniProt ID Q9UHC1
Synonyms HNPCC7
Summary This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN412150 MLH3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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