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Human ITGB1BP2 activation kit by CRISPRa

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SKU
GA108902
ITGB1BP2 CRISPRa kit - CRISPR gene activation of human integrin subunit beta 1 binding protein 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
$525.00
RC215481 ITGB1BP2 (Myc-DDK-tagged)-Human integrin beta 1 binding protein (melusin) 2 (ITGB1BP2)
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Other products for "ITGB1BP2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITGB1BP2
Locus ID 26548
Components

GA108902G1, ITGB1BP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108902G2, ITGB1BP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108902G3, ITGB1BP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001303277, NM_012278
UniProt ID Q9UKP3
Synonyms CHORDC3; ITGB1BP; MELUSIN; MSTP015
Summary This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. provided by RefSeq, May 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN415481 ITGB1BP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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