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Human Hsp22 (HSPB8) activation kit by CRISPRa

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SKU
GA108860
HSPB8 CRISPRa kit - CRISPR gene activation of human heat shock protein family B (small) member 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA501210 HSPB8 (Hsp22) mouse monoclonal antibody, clone OTI1E3 (formerly 1E3) 100 ul
$447.00
RC201040 HSPB8 (Myc-DDK-tagged)-Human heat shock 22kDa protein 8 (HSPB8)
10 ug
$450.00

Other products for "HSPB8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HSPB8
Locus ID 26353
Components

GA108860G1, Hsp22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108860G2, Hsp22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108860G3, Hsp22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014365
UniProt ID Q9UJY1
Synonyms CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
Summary The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN401040 HSPB8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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