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Human BRDG 1 (STAP1) activation kit by CRISPRa

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SKU
GA108804
STAP1 CRISPRa kit - CRISPR gene activation of human signal transducing adaptor family member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC204854 STAP1 (Myc-DDK-tagged)-Human signal transducing adaptor family member 1 (STAP1)
10 ug
$300.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STAP1
Locus ID 26228
Components

GA108804G1, BRDG 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108804G2, BRDG 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108804G3, BRDG 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001317769, NM_012108
UniProt ID Q9ULZ2
Synonyms BRDG1; STAP-1
Summary The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015
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Documents
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Other Versions
SKU Description Size Price
KN404854 STAP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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