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Human HERC4 activation kit by CRISPRa

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SKU
GA108745
HERC4 CRISPRa kit - CRISPR gene activation of human HECT and RLD domain containing E3 ubiquitin protein ligase 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC211865 HERC4 (Myc-DDK-tagged)-Human hect domain and RLD 4 (HERC4), transcript variant 1
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Other products for "HERC4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HERC4
Locus ID 26091
Components

GA108745G1, HERC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108745G2, HERC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108745G3, HERC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001017972, NM_001278185, NM_001278186, NM_001278187, NM_015601, NM_022079
UniProt ID Q5GLZ8
Synonyms DKFZP564G092; KIAA1593
Summary HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 PubMed 15676274).supplied by OMIM, Mar 2008
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Documents
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Other Versions
SKU Description Size Price
KN408071 HERC4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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