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Human ABHD12 activation kit by CRISPRa

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SKU
GA108744
ABHD12 CRISPRa kit - CRISPR gene activation of human abhydrolase domain containing 12
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC216963 ABHD12 (Myc-DDK-tagged)-Human abhydrolase domain containing 12 (ABHD12), transcript variant 1
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Other products for "ABHD12"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ABHD12
Locus ID 26090
Components

GA108744G1, ABHD12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108744G2, ABHD12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108744G3, ABHD12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001042472, NM_015600
UniProt ID Q8N2K0
Synonyms ABHD12A; BEM46L2; C20orf22; dJ965G21.2; PHARC
Summary This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.provided by RefSeq, Jan 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN404302 ABHD12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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