Human PPP1R16B activation kit by CRISPRa

SKU GA108723

PPP1R16B CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 16B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PPP1R16B
• Locus ID: 26051
• Components:

  GA108723G1, PPP1R16B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108723G2, PPP1R16B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108723G3, PPP1R16B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001172735, NM_015568
• UniProt ID: Q96T49
• Synonyms: ANKRD4; TIMAP
• Summary: The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]