Human NECAP1 activation kit by CRISPRa

SKU GA108670

NECAP1 CRISPRa kit - CRISPR gene activation of human NECAP endocytosis associated 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NECAP1
• Locus ID: 25977
• Components:

  GA108670G1, NECAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108670G2, NECAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108670G3, NECAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015509, NR_024260
• UniProt ID: Q8NC96
• Synonyms: EIEE21
• Summary: This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]