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Human VIRMA activation kit by CRISPRa

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SKU
GA108661
VIRMA CRISPRa kit - CRISPR gene activation of human vir like m6A methyltransferase associated
  $1,657.00
4 Weeks*

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Other products for "VIRMA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol VIRMA
Locus ID 25962
Components

GA108661G1, VIRMA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108661G2, VIRMA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108661G3, VIRMA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_015496, NM_183009
UniProt ID Q69YN4
Synonyms fSAP121; MSTP054
Summary Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:24981863, PubMed:29507755). Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3' UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites (PubMed:29507755). Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3' UTR near the stop codon correlating with alternative polyadenylation (APA) (PubMed:29507755).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN422516 KIAA1429 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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