Human TRIM58 activation kit by CRISPRa

SKU GA108610

TRIM58 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 58

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TRIM58
• Locus ID: 25893
• Components:

  GA108610G1, TRIM58 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108610G2, TRIM58 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108610G3, TRIM58 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015431
• UniProt ID: Q8NG06
• Synonyms: BIA2
• Summary: E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.[UniProtKB/Swiss-Prot Function]