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Human TPSG1 activation kit by CRISPRa

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SKU
GA108563
TPSG1 CRISPRa kit - CRISPR gene activation of human tryptase gamma 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA504161 TPSG1 mouse monoclonal antibody, clone OTI1G1 (formerly 1G1) 100 ul
$447.00
RC222359 TPSG1 (Myc-DDK-tagged)-Human tryptase gamma 1 (TPSG1)
10 ug
$300.00

Other products for "TPSG1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TPSG1
Locus ID 25823
Components

GA108563G1, TPSG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108563G2, TPSG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108563G3, TPSG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_012467
UniProt ID Q9NRR2
Synonyms PRSS31; TMT; trpA
Summary Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN422359 TPSG1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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