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Human IL17RA activation kit by CRISPRa

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SKU
GA108494
IL17RA CRISPRa kit - CRISPR gene activation of human interleukin 17 receptor A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC202390 IL17RA (Myc-DDK-tagged)-Human interleukin 17 receptor A (IL17RA)
10 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL17RA
Locus ID 23765
Components

GA108494G1, IL17RA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108494G2, IL17RA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108494G3, IL17RA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001289905, NM_014339
UniProt ID Q96F46
Synonyms CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
Summary Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Feb 2014
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Other Versions
SKU Description Size Price
KN402390 IL17RA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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