Human PKC nu (PRKD3) activation kit by CRISPRa

SKU
GA108475
PRKD3 CRISPRa kit - CRISPR gene activation of human protein kinase D3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRKD3
Locus ID 23683
Components

GA108475G1, PKC nu gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108475G2, PKC nu gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108475G3, PKC nu gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005813
UniProt ID O94806
Synonyms EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN
Summary This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. provided by RefSeq, Jan 2015
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Documents
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Other Versions
SKU Description Size Price
KN421309 PRKD3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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