Human PLD3 activation kit by CRISPRa

SKU GA108458

PLD3 CRISPRa kit - CRISPR gene activation of human phospholipase D family member 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PLD3
• Locus ID: 23646
• Components:

  GA108458G1, PLD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108458G2, PLD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108458G3, PLD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001031696, NM_001291311, NM_012268
• UniProt ID: Q8IV08
• Synonyms: AD19; HU-K4; HUK4
• Summary: This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]