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Human SH3BP1 activation kit by CRISPRa

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SKU
GA108436
SH3BP1 CRISPRa kit - CRISPR gene activation of human SH3 domain binding protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC219860 SH3BP1 (Myc-DDK-tagged)-Human SH3-domain binding protein 1 (SH3BP1)
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Other products for "SH3BP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SH3BP1
Locus ID 23616
Components

GA108436G1, SH3BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108436G2, SH3BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108436G3, SH3BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_018957, NM_032201, NM_001350055
UniProt ID Q9Y3L3
Synonyms ARHGAP43
Summary This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN419860 SH3BP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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