Human QPRT activation kit by CRISPRa

SKU
GA108332
QPRT CRISPRa kit - CRISPR gene activation of human quinolinate phosphoribosyltransferase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol QPRT
Locus ID 23475
Components

GA108332G1, QPRT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA108332G2, QPRT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA108332G3, QPRT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001318249, NM_001318250, NM_014298, NR_134536
UniProt ID Q15274
Synonyms HEL-S-90n; QPRTase
Summary This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015
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Other Versions
SKU Description Size Price
KN402960 QPRT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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