Human OBSL1 activation kit by CRISPRa

SKU GA108251

OBSL1 CRISPRa kit - CRISPR gene activation of human obscurin like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: OBSL1
• Locus ID: 23363
• Components:

  GA108251G1, OBSL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108251G2, OBSL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108251G3, OBSL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001173408, NM_001173431, NM_015311
• UniProt ID: O75147
• Synonyms: KIAA0657; MGC71026
• Summary: Cytoskeletal adaptor proteins function in linking the internal cytoskeleton of cells to the cell membrane. This gene encodes a cytoskeletal adaptor protein, which is a member of the Unc-89/obscurin family. The protein contains multiple N- and C-terminal immunoglobulin (Ig)-like domains and a central fibronectin type 3 domain. Mutations in this gene cause 3M syndrome type 2. Alternatively spliced transcript variants encoding different isoforms have been found in this gene. [provided by RefSeq, Mar 2010]