Human CAMTA1 activation kit by CRISPRa

SKU GA108171

CAMTA1 CRISPRa kit - CRISPR gene activation of human calmodulin binding transcription activator 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CAMTA1
• Locus ID: 23261
• Components:

  GA108171G1, CAMTA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108171G2, CAMTA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108171G3, CAMTA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001195563, NM_001242701, NM_015215, NR_038934, NM_001349608, NM_001349609, NM_001349610, NM_001349612, NM_001349613, NM_001349614, NM_001349615, NM_001349616, NM_001349617, NM_001349618, NM_001349619, NM_001349620, NM_001349621, NM_001349622, NM_001349623, NM_001349624, NM_001349625, NM_001349626, NM_001349627, NR_146202, NR_146203, NR_146204
• UniProt ID: Q9Y6Y1
• Synonyms: CANPMR
• Summary: The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]