Human ANKRD12 activation kit by CRISPRa

SKU GA108165

ANKRD12 CRISPRa kit - CRISPR gene activation of human ankyrin repeat domain 12

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ANKRD12
• Locus ID: 23253
• Components:

  GA108165G1, ANKRD12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108165G2, ANKRD12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108165G3, ANKRD12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001083625, NM_001204056, NM_015208
• UniProt ID: Q6UB98
• Synonyms: ANCO-2; ANCO1; GAC-1; Nbla00144
• Summary: This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]