Human SCC112 (PDS5A) activation kit by CRISPRa

SKU GA108157

PDS5A CRISPRa kit - CRISPR gene activation of human PDS5 cohesin associated factor A

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PDS5A
• Locus ID: 23244
• Components:

  GA108157G1, SCC112 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108157G2, SCC112 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108157G3, SCC112 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001100399, NM_001100400, NM_015200
• UniProt ID: Q29RF7
• Synonyms: PIG54; SCC-112; SCC112
• Summary: The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]